CAPILLARY ZONE ELECTROPHORESIS OF PATHOLOGICAL METABOLITES IN PHENYLKETONURIA

Authors
Citation
V. Dolnik, CAPILLARY ZONE ELECTROPHORESIS OF PATHOLOGICAL METABOLITES IN PHENYLKETONURIA, The Journal of microcolumn separations, 6(1), 1994, pp. 63-67
Citations number
18
Categorie Soggetti
Chemistry Analytical
ISSN journal
10407685
Volume
6
Issue
1
Year of publication
1994
Pages
63 - 67
Database
ISI
SICI code
1040-7685(1994)6:1<63:CZEOPM>2.0.ZU;2-M
Abstract
The pathological metabolites (phenylpyruvate, 2-hydroxyphenylacetate, phenyllactate, and phenylacetate) from urine of phenyllketonuric indiv iduals were separated by capillary zone electrophoresis within 12 minu tes. Significant differences in the content of these metabolites in ur ine can be found ifa healthy man, a phenylketonuric newborn, and a phe nylketonuric individual on a low-phenylalanine diet are compared.