NEW 5-SUBSTITUTED DERIVATIVES OF ETHYL -DIHYDRO-3-OXOISOTHIAZOLO[5,4-B]PYRIDINE-2-ACETATE

Authors
MARTINEZMERINO V GIL MJ GONZALEZ A ZABALZA JM NAVARRO J MANU MA
Citation
V. Martinezmerino et al., NEW 5-SUBSTITUTED DERIVATIVES OF ETHYL -DIHYDRO-3-OXOISOTHIAZOLO[5,4-B]PYRIDINE-2-ACETATE, Heterocycles, 38(2), 1994, pp. 333-344
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
38
Issue
2
Year of publication
1994
Pages
333 - 344
Database
ISI
SICI code
0385-5414(1994)38:2<333:N5DOE->2.0.ZU;2-C
Abstract
New series of ethyl 5-substituted 2,3-dihydro-3-oxoisothiazolo[5,4-b] pyridine-2-acetate was prepared either a) directly by reaction of 5-su bstituted 2-chlorothio-3-pyridinecarbonyl chlorides with ethyl glycina te or b) by oxidation of the correspondent 2-mercapto-3-pyridinecarbox amides. New 5-substituted 1,2-dihydro-2-thioxo-3-pyridinecarboxylic ac ids as starting materials are described.