Despite a consensus view that we are experiencing an epidemic of drug
and alcohol abuse in adolescents, there is little agreement about the
definition of adolescent substance abuse disorders. This review explor
es past and current efforts at defining psychoactive substance use pro
blems and the relevance of these efforts to adolescents. Current diagn
ostic classifications and criteria for substance abuse and dependence
are often inadequate in describing the clinically relevant patterns of
substance use in adolescents. A discussion of future directions in th
e nosology of adolescent substance abuse focuses on the need for the d
evelopment of a valid, meaningful classification system for substance
use problems, using data from studies of prevalence, natural history,
genetics, and treatment outcome among youth.