The past year has seen many developments in our understanding of the c
linical patterns of genital herpes, including asymptomatic carriage an
d transmission, These issues raise concerns about transmission and con
tribute significantly to the psychosocial impact of this disease. Mana
gement strategies are rapidly changing as we enter the era of possible
vaccine intervention. Management during pregnancy continues to raise
controversies, stimulating the Infectious Diseases Society of America
to publish official recommendations. New data, however, show us that h
ealth care providers are doing a relatively poor job of giving appropr
iate care and emotional support to patients in need. Similarly, human
papilloma virus infections can also be missed on a clinical basis. Inf
ection may be multifocal nature and even oral. Psychosocial impact can
be severe with this incurable virus. Its correlation with cervical an
d vulvar neoplasia becomes more evident, while management strategies a
ddress only the majority of clinical warts leaving much to be desired.