Few reports have described the psychiatric co-morbidity of Noonan synd
rome. While mental retardation is a common feature of Noonan syndrome,
the diagnosis of autism using operational criteria has not been repor
ted. In this paper, the authors describe the association of Noonan syn
drome with autism. They propose that the co-morbid diagnosis of autism
should be considered during the clinical assessment of persons with N
oonan syndrome.