Jt. Williams et al., PAPULONECROTIC TUBERCULID SECONDARY TO DISSEMINATED MYCOBACTERIUM-AVIUM COMPLEX, International journal of dermatology, 33(2), 1994, pp. 109-112
Background. Papulonecrotic tuberculid is a rarely reported cutaneous r
eaction to the mycobacterium bacillus. It is most often encountered in
association with tuberculosis. The clinical and histologic picture of
the entity is a distinctive one, but the etiology of the disease proc
ess is uncertain. Therapy directed against the causative organism is d
ramatically successful. Methods. A 35-year-old white man with AIDS was
referred to the Dermatology clinic for evaluation of a widespread ski
n eruption. The skin lesions were biopsied for histopathology and cult
ure. From the cutaneous cultures Mycobacterium avium complex (MAC) org
anisms were grown. Results. We report the first case of papulonecrotic
tuberculid Manifestation in an AIDS patient with disseminated MAC. Un
usual features seen in this case include the predominance of pruritic
eschars rather than asymptomatic papules and the confirmation by speci
al stains of mycobacterium organisms within the skin biopsy. Papulonec
rotic tuberculid has not been previously associated with either MAC or
AIDS. Conclusions. Papulonecrotic tuberculid should be a diagnostic c
onsideration in immunocompromised patients with MAC Whose clinical and
histologic features are compatible with this rare entity.