TRANSITIONAL-CELL CARCINOMA OF FOSSA-NAVICULARIS IN A MAN WITH 3 OTHER SYNCHRONOUS MALIGNANCIES

Transitional cell carcinoma arising from the anterior portion of the m ale urethra is rare, with less than 10 cases reported in the literatur e. Our patient had a high-grade, highly invasive transitional cell car cinoma originating in the fossa navicularis and extending proximally a long the corpus spongiosum, the corpora cavernosa, and blood and lymph atic vessels. In addition, the patient had a concurrent low-grade pros tatic adenocarcinoma, a large basal cell carcinoma of the nose, and a squamous cell carcinoma of the penile skin. The previously reported ca ses are reviewed, with particular reference to the possible associatio n of these tumors with human papillomavirus infection.