DIETARY HABITS IN CALCIUM-OXALATE AND CAL CIUM-PHOSPHATE STONE FORMERS

In order to better understand the role of diet in etiology of urolithi asis, 84 oxalo-phospho-calcic-lithiasic patients (52 men,32 women) hav e been studied by a nutritional week-interview and by urinary and bloo d testing. Diet data were compared to an ideal standard. Total caloric intake was 2428 +/- 651 calories/d, this intake is high in 7% women a nd 40% men. 79% out of patients are fat. Protidic intake is 87 +/- 21 g/d higher than 1 g/kg/d in 84,5% of patients. Lipids are high in 38,9 +/- 7%, glucid are low in 45,3 +/- 7%. Calcium intake is 934 +/- 406 mg/d, sodium intake is 12,9 + 3 g/d. Water intake is 2305 +/- 759 ml/d . Different groups of patients are studied: a) 21 patients with mean a ge of 43 +/- 12 years have recurrent lithiasis (R). This group is comp ared to 48 patients with 37 +/- 44 years who have a single lithiasis. Half of (R) patients have hypercalciuria, hyperphosphaturia and hypero xaluria. Diet study is no different between these two groups. b) Other groups are studied: 21 have hyperphosphaturia (HPU) without hypophosp horemia and they have hypercalciuria, hyperuraturia and high urinary u rea; diet shows higher glucicid and potassium intake than group with n ormal phosphaturia; 23 have hypercalciuria (HCU) and high uraturia and phosphaturia: diet study shows no difference with a group with normal calciuria. 21 have hyperoxaluria (HOU): diet study of a normal oxalur ic group shows higher lipid intake, lower glucidic and calcium intake; 22 have hyperuraturia (HAU) and higher urinary urea, sodium and potas sium than normouraturia group: in this group potassium intake is highe r. Among these groups,men are predominant [GRAPHICS] Differences betwe en results of nutritional interwiew and urinary biology raise question elective modification of tubular handling in lithiasic patients. Sign ificant relationship has been found between urinary urea and calciuria , phosphaturia, uraturia and natriuria. Citraturia correlated positive ly with kaliuria and natriuria. Finaly, diet study and metabolic study of urolithiasic risk factors allow good prevention, but activity dise ase is not exclusively related to nutritional factors and it seems to be dependent of many factors who deserve to be individualised.