A random sample of 3258 adult household residents of Edmonton, Alberta
, Canada were interviewed by trained lay interviewers using the Diagno
stic Interview Schedule (DIS), which gives DSM-III diagnostic data on
each individual interviewed. This paper reports results for panic diso
rder. Panic disorder was found to affect women primarily (female:male
morbidity risk 2.2:1). The mean age of onset (first symptom) was 19.3
years for men and 21.5 years for women. Rarely did symptoms first occu
r after the age of forty. The lifetime prevalence rate was 1.7% for wo
men and 0.8% for men and the lifetime morbidity risk was 3.7% for fema
les and 1.7% for males. All twelve panic symptoms were found to be hig
hly specific for panic disorder. Women complained of more (means = 8.0
) symptoms than men (means = 6.0). On average 7.3 symptoms were report
ed. Those with panic disorder showed increased lifetime prevalence rat
es for major depressive episode (73.4%), alcohol abuse/dependence (54.
2%), drug abuse/dependence (43%) and phobia (44.2%). Altogether, 90.4%
of those with panic disorder also met criteria for another DSM-III di
agnosis, which was 2.7 times the rate in those who did not have panic
disorder.