The first part of this paper provides a general outline of objectives
and methods of the Internal Illedicine and Geriatrics Unit of the Berl
in Aging Study (BASE). Based on a multi-dimensional conceptualization
of health, objective and laboratory data collected about different org
an systems, e.g. cardiovascular and musculoskeletal, and functional ca
pacity are complemented by qualitative clinical diagnoses and judgemen
ts as well as self-reported health problems and functional limitations
. Some of the central questions that can be addressed using these data
relate to understanding the nature and processes of differential agei
ng. The second part of the paper includes initial analyses of inter-in
dividual health differences in advanced old age (70 to 105 years). Ini
tial findings indicated that heterogeneity in somatic morbidity and fu
nctional capacity was at least as large in old adults (70 to 84 years)
as in very old adults (85 to 105 years), even though higher rates of
somatic morbidity and lower levels of functional capacity were observe
d in the very old. Chronological age and morbidity as well as psychoso
cial and demographic factors were found to be independent predictors o
f functional capacity in advanced old age. Additionally, the relative
importance of psychosocial factors was found to be a function of age w
ith lower predictive ability among the very old. In conclusion, these
initial findings support the hypothesis of significant health differen
ces in advanced old age due to differential ageing.