Da. Clark et al., SYMPTOM DIFFERENCES IN MAJOR DEPRESSION, DYSTHYMIA, PANIC DISORDER, AND GENERALIZED ANXIETY DISORDER, The American journal of psychiatry, 151(2), 1994, pp. 205-209
Objective: The authors compared symptom features of specific subtypes
of depressive and anxiety disorders. Method: Psychiatric outpatients w
ith moderate levels of psychopathology and DSM-III diagnoses of major
depression, dysthymia, panic disorder, or generalized anxiety disorder
were given five standard measures of symptoms of anxiety and depressi
ve disorders. Most of the outpatients were white, and most were middle
-class. Results: Principal components analysis revealed 12 orthogonal
symptom components. Discriminant function analysis indicated that anxi
ety was distinguished by specific autonomic arousal symptoms, threat-r
elated cognitions, and subjective anxiety and tension. Discriminant fu
nction analysis also indicated that depression was distinguished by an
hedonia, cognitions of personal loss and failure, and dysphoric mood.
Conclusions: As nosological categories, major depression and panic dis
order were better differentiated by specific symptom markers than dyst
hymia and generalized anxiety disorder.