CELL COMPOSITION OF UMBILICAL-CORD BLOOD IN PATHOLOGICAL AND PHYSIOLOGICAL PREGNANCY

Possible influence of most frequently encounted types of pathology dur ing pregnancy on the cell composition of umbilical cord blood was stud ied. These pathologies included: treated iron-deficiency anemia, essen tial hypertension, threatening spontaneous abortion. A number and prol iferative potential of granulocyte-macrophage precursor cells of umbil ical cord blood were studied by agar drop-liquid media culture method. It was found that the types of pathology studied do not influence cel l composition, number and proliferative potential of granulocyte-macro phage precursor cells from umbilical cord brood. These results show th at umbilical cord blood after pathological pregnancy can be considered as a sourse of transplantable hemopoietic cells.