A PECULIAR COURSE OF CHRONIC GENERALIZED HBV INFECTION - CLINICOMORPHOLOGICAL EVALUATION

In a young male chronic generalized HBV infection (acute viral hepatit is in childhood, HBsAg, HBeAb, HBcAb in the blood serum) ran with a lo ng-term fever and involvement of many organs and systems (the liver, l ungs, CNS) complicating the diagnosis. The patient died in the presenc e of CNS affection and hepatorenal insufficiency. At biopsy and autops y it was established that the patient had active hepatic cirrhosis, fi brosing alveolitis, pulmonary vasculitides, chronic pneumonia, cerebra l vasculitis, myocarditis and postmyocarditis cardiosclerosis, necroti zing myositis, Sjogren's syndrome, mesangioproliferative glomeruloneph ritis.