METALATION OF TRIAZINES .2. SYNTHESIS OF BI-1,2,4-TRIAZINES AND 1,2,4-TRIAZINE-6-CARBALDEHYDES

Authors
GLASSL B SINKS U NEUNHOEFFER H
Citation
B. Glassl et al., METALATION OF TRIAZINES .2. SYNTHESIS OF BI-1,2,4-TRIAZINES AND 1,2,4-TRIAZINE-6-CARBALDEHYDES, Heterocyclic communications, 2(6), 1996, pp. 513-520
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocyclic communications → ACNP
ISSN journal
07930283
Volume
2
Issue
6
Year of publication
1996
Pages
513 - 520
Database
ISI
SICI code
0793-0283(1996)2:6<513:MOT.SO>2.0.ZU;2-J
Abstract
5-Methoxy-6H-1,2,4-triazines 1a-c, 5H-1,2,4-triazine-6-diethylcarboxam ides 7a,b and 3,6-diphenyl-1,2,4-triazine 4-oxide 10 were lithiated wi th lithium 2,2,6,6-tetramethylpiperidide and the formed lithio-1,2,4-t riazines 2a-c, 8a, b, 11 reacted with chlorotrimethylsilane and other reagents to give the bi-1,2,4-triazines 3a-c,4a, b, 12, 13. 6-Lithio-1 ,2,4-triazines 2a, b afforded 3a, b and 5-methoxy-1,2,4-triazine-6-car baldehydes 5a, b when reacted with N-formylpiperidine or ethyl formate .