We conducted a case-control study of the possible association of occup
ations with likely exposure to electromagnetic fields and Alzheimer's
disease (AD) with patients from the Alzheimer Disease Treatment and Di
agnostic Center, Rancho Los Amigos Medical Center, Downey, CA. Patient
s with definite or probable AD were the case subjects (86 male, 240 fe
male). Patients with cognitive impairment/dementia other than vascular
dementia were control subjects (76 male, 76 female). The study was li
mited to patients who were at least age 65 at the time of their first
examination at Rancho Los Amigos. The odds ratio for both sexes combin
ed was adjusted for sex, education, and age at onset. The odds ratio f
or males was adjusted only for age at onset, and the odds ratio for fe
males was adjusted for both education and age at onset. The adjusted o
dds ratio for both sexes was 3.93 (p = 0.006), 95% CI = (1.5 to 10.6).
For males the adjusted odds ratio was 4.90 (p = 0.01), 95% CI = (1.3
to 7.9), and for females the adjusted odds ratio was 3.40 (p = 0.10),
95% CI = (0.8 to 16.0). These results are consistent with previous fin
dings regarding the hypothesis that electromagnetic field exposure is
etiologically associated with the occurrence of AD.