A study of endoscopic carpal tunnel release was carried out in three p
arts, consisting of initial cadaveric dissections, a prospective pilot
study of 20 patients and a prospective, randomized trial of 71 patien
ts comparing endoscopic with open decompression. In the main trial, 25
patients with bilateral symptoms underwent simultaneous endoscopic an
d open release, with the remainder randomized to one or other techniqu
e. Both techniques effectively decompressed the median nerve. A signif
icant improvement in grip and pinch strength over 3 months was achieve
d in those undergoing endoscopic surgery. Average return to work was 1
4 days in the endoscopic series and 39 days in the open series. A comp
lication rate of 35% was achieved with the transbursal endoscopic tech
nique, 3.7% with the extrabursal endoscopic technique and 13.5% in the
open series.