Education and training in self-management of blood glucose control has
become a permanent task for all people involved in the care of diabet
ic patients. Since this may be facilitated by applying state-of-the-ar
t information technology, we have developed the decision support syste
m KADIS (Karlsburg Diabetes Management System), It comprises computer-
aided tools for (1) the evaluation (selection, aggregation, storage, s
tatistics, graphics) of therapeutic data, e.g. from patients' logbooks
, and (2) the simulation of daily profiles of glycaemia and insulinaem
ia on the basis of a mathematical model of the glucose-insulin regulat
ory system, parameters of which can be adapted to the characteristics
of individual patients. The latter tool allows the patient to predict
his response to any modification in the therapeutic regime and to lear
n how variations in timing, formulation and doses of insulin, in carbo
hydrate equivalents and absorption characteristics of meals, and in ex
ercise may influence the daily pattern in glycaemia. This procedure ha
s been well accepted as an educational tool by those patients who were
`self-managing' their metabolic control.