Duplex Doppler sonography (DDS) and angiography were per formed in a p
rospective study comprising 22 adult patients with hepatic failure. Th
e ability of the 2 methods to Visualize the different splanchnic Vesse
ls was compared, as well as any abnormality in the liver parenchyma an
d vessels. The purpose of the study was to decide if DDS could replace
angiography in the pretransplantation work-up in these patients. The
portal vein was correctly identified as open in 20 patients using DDS
and in 21 patients at angiography. Portal Vein thrombosis in one patie
nt was correctly diagnosed by both methods. The identification of othe
r vascular structures in the upper part of the abdomen, e.g., liver ar
teries and splenic vein, was demonstrated in 14 and 16 patients respec
tively at DDS. Hepatoma in one patient was correctly identified by bot
h methods, as well as the presence of ascites. Splenic artery aneurysm
s were found in 4 patients at angiography, and in none of these was DD
S able to show this abnormality. We conclude that abdominal angiograph
y still seems superior to DDS in the evaluation of patients with hepat
ic failure prior to orthotopic liver transplantation, especially to de
monstrate possible splenic artery aneurysms and detailed mapping of th
e hepatic arteries.