THE EFFECT OF MIANSERIN AND ADDITIONAL FL UID INTAKE IN ELDERLY DEPRESSIVE PATIENTS, WITH PARTICULAR REFERENCE TO THE BLOOD UREA CONTENT

Authors
WIESELMANN G FABISCH H HERZOG G FABISCH K PROBST C LANGS G ZAPOTOCZKY HG
Citation
G. Wieselmann et al., THE EFFECT OF MIANSERIN AND ADDITIONAL FL UID INTAKE IN ELDERLY DEPRESSIVE PATIENTS, WITH PARTICULAR REFERENCE TO THE BLOOD UREA CONTENT, Wiener Klinische Wochenschrift, 106(3), 1994, pp. 89-91
Citations number
11
Categorie Soggetti
Medicine, General & Internal
Journal title
Wiener Klinische Wochenschrift → ACNP
ISSN journal
00435325
Volume
106
Issue
3
Year of publication
1994
Pages
89 - 91
Database
ISI
SICI code
0043-5325(1994)106:3<89:TEOMAA>2.0.ZU;2-2
Abstract
36 elderly outpatients (mean age 68.6 years) with depression and incre ased blood urea level were treated with mianserin (60 mg every evening ). All patients were ordered to drink additionally 1l of mineral water per day, which only 30 patients complied with. The patients who compl ied with the ordered increase in fluid intake (responder, n = 30) show ed in comparison to those who did not comply (non-responder, n = 6) a significant improvement in depression (i.e., HAM-D, p < 0.001) after a four week period of treatment (t2). The responders' blood urea level normalized whereas the non-responders' level, although lowered, still remained in the pathological range.