Objective The results of proximal splenorenal shunts done in children
with extrahepatic portal venous obstruction were evaluated. Summary Ba
ckground Data Extrahepatic portal venous obstruction, a common cause o
f portal hypertension in children in India, is being treated increasin
gly by endoscopic sclerotherapy instead of by proximal splenorenal shu
nt. It is believed that surgery (or the operation) carries high mortal
ity and rebleeding rates and is followed by portosystemic encephalopat
hy and postsplenectomy sepsis. However, a proximal splenorenal shunt i
s a definitive procedure that may be more suitable for children, parti
cularly those who have limited access to medical facilities and safe b
lood transfusion. Methods Between 1976 and 1992, the authors performed
160 splenorenal shunts in children. Twenty were emergency procedures
for uncontrollable bleeding and 140 were elective procedures - 102 for
recurrent bleeding and 38 for hypersplenism. Results The overall oper
ative mortality rate was 1.9%-10% (3/160-2/20) after emergency operati
ons and 0.7% (1/140) after elective operations. Rebleeding occurred in
17 patients (11%), and pneumococcal meningitis developed in 1 patient
who recovered later. Encephalopathy did not develop in any patient. F
our patients died in the follow-up period - two of rebleeding, one of
chronic renal failure and a subphrenic abscess, and one of unknown cau
ses. The 15-year survival rate by life table analysis was 95%. Conclus
ions A proximal splenorenal shunt, a one-time procedure with a low mor
tality rate and good long-term results, is an effective treatment for
children in India with extrahepatic portal venous obstruction.