G. Alperstein et al., THE PREVALENCE OF TUBERCULOSIS INFECTION AMONG YEAR 8 SCHOOLCHILDREN IN INNER SYDNEY IN 1992, Medical journal of Australia, 160(4), 1994, pp. 197-201
Objective: To determine the prevalence of tuberculosis (TB) infection
in Year 8 schoolchildren (aged 12-14 years) in Sydney. Design: Cross-s
ectional survey. Setting: 22 inner city Sydney secondary schools. Part
icipants: 2290 Year 8 school children enrolled in 1992. Outcome measur
es: Distribution of Mantoux test reaction size and proportion of child
ren who were Mantoux positive (i.e., having Mantoux reaction greater t
han or equal to 15 mm with previous Bacille Calmette-Guerin vaccinatio
n; greater than or equal to 10 mm without). Results: Of the 2290 child
ren, 1836 (81%) were screened and 1801 Mantoux reactions were read. Te
n per cent of children were Mantoux positive -27% of foreign-born chil
dren and 2% of Australian-born children (relative risk 16.7, 95% confi
dence interval 10.6-26.4). Two children were found to have active TB d
isease. Conclusion: There is a high prevalence of primary (non-contagi
ous) TB infection in children aged 12-14 years in inner Sydney, mostly
confined to children born overseas. Thus there is a large pool of inf
ected children at risk of developing active (contagious) adult-type TB
disease in the future. This public health problem should be addressed
by identification and treatment of those infected.