L. Duntas et al., ATRIAL NATRIURETIC PEPTIDE-LIKE IMMUNOREACTIVE MATERIAL (ANP-LI) IS RELEASED FROM THE ADRENAL-GLAND BY SPLANCHNIC NERVE-STIMULATION, Experimental and clinical endocrinology, 101(6), 1993, pp. 371-373
We investigated the release of atrial natriuretic peptide-like immunor
eactive material (ANP-LI) after splanchnic nerve stimulation of isolat
ed perfused adrenal glands. Electrical stimulation of the splanchnic n
erves caused a statistically significant increase of ANP-LI (186 +/- 1
2 pg. min(-1); p < 0.05) at 5 min. after stimulation. The integrated A
NP-LI release after stimulation was amounted to 354 +/- 6.8% over basa
l. The regulation of ANP through the sympathoadrenal system may indica
te an important role of ANP in adrenal steroidogenesis.