Jl. Soengas et al., FOOD-DEPRIVATION AND REFEEDING IN ATLANTIC SALMON, SALMO-SALAR - EFFECTS ON BRAIN AND LIVER CARBOHYDRATE AND KETONE-BODIES METABOLISM, Fish physiology and biochemistry, 15(6), 1996, pp. 491-511
The capacity of carbohydrate and ketone bodies metabolism in brain and
liver was evaluated in fed and food-deprived Atlantic salmon (Salmo s
alar) in a time period covering from 1 to 7 days (Experiment I), and i
n Atlantic salmon food deprived for 6 weeks, and food deprived for 4 w
eeks and refed for 2 weeks (Experiment II), The results obtained demon
strate for the first time in a teleost the existence of changes in bra
in metabolism due to food deprivation. Thus, decreased glucose levels
in plasma are reflected in the brain by an increased mobilization of g
lycogen reserves, and by a decreased glycolytic capacity. Also, ketone
bodies appear to increase their importance as a metabolic fuel from d
ay 7 of food deprivation onwards. A possible increase in the gluconeog
enic potential in brain simultaneously is not discarded. All these met
abolic changes are reversed under refeeding conditions.