Thirty acutely schizophrenic inpatients each provided two speech sampl
es: one on affectively negative, ''high-stress'' topics and one on aff
ectively positive, ''low-stress'' topics. We analyzed these using two
different, established methods for assessment of deviance in natural l
anguage, including clinical measures of thought disorder and linguisti
c measures of reference performance. For the group as a whole, the spe
ech on negative topics contained more disorder than did the speech on
positive topics, as rated both clinically and linguistically, and thes
e differences mere sizeable and highly significant, Level of language
disturbance and degree of affective reactivity of language symptoms co
rrelated positively with severity of the positive syndrome but were no
t associated in either direction with negative syndrome severity. Affe
ctive reactivity of symptoms is discussed as a variable potentially re
levant to studies of psychophysiology and subtyping, in schizophrenia