MOLECULAR-CLONING OF AN ALPHA(1)-SUBUNIT FROM HOUSEFLY (MUSCA-DOMESTICA) MUSCLE

Authors
GRABNER M BACHMANN A ROSENTHAL F STRIESSNIG J SCHULZ C TAUTZ D GLOSSMANN H
Citation
M. Grabner et al., MOLECULAR-CLONING OF AN ALPHA(1)-SUBUNIT FROM HOUSEFLY (MUSCA-DOMESTICA) MUSCLE, FEBS letters, 339(1-2), 1994, pp. 189-194
Citations number
46
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
339
Issue
1-2
Year of publication
1994
Pages
189 - 194
Database
ISI
SICI code
0014-5793(1994)339:1-2<189:MOAAFH>2.0.ZU;2-E
Abstract
The complete amino acid sequence of an invertebrate calcium channel al pha-subunit from housefly (Musca domestica) larvae (designated Mdl alp ha(1)) has been deduced by cDNA cloning and sequence analysis. Mdbl al pha(1) shares higher percent sequence identity with 1,4-dihydropyridin e (DHP)-sensitive L-type than with DHP-insensitive calcium channels. A s shown by whole mount in situ hybridization and immunostaining Mdl al pha(1) is predominantly expressed in the larval body wall musculature.