The true incidence of bedside transfusion errors, i.e. those happening
when blood products have left the blood bank, is underestimated becau
se published figures rely on reporting of clinically relevant events o
r on indirect methods. The SANGUIS project assessing blood practice in
a prospective and randomized fashion for 6 elective surgical procedur
es gave the opportunity to trace all transfused units and to identify
steps at risk during blood delivery in surgery. We considered transfus
ion of a wrong unit as a major error and poor execution or documentati
on as a recording error. Over 15 months, 808 patients out of 1,448 wer
e transfused with 3,485 units. A total of 165 errors were found after
blood products had left the blood banks. Seven were misidentifications
(0.74% of patients, 0.2% of units). Eight other major errors occurred
in 4 (0.5%) patients. Major errors occurred during nonemergency situa
tions, in wards or intensive care units. The remaining ('recording') 1
50 errors consisted of misrecordings (61), mislabellings (6), or failu
res to document transfusions in the medical records (83). All errors w
ere uneventful except one misidentification which induced a transient,
yet unreported, reaction. The 'descending' inquiry method used for th
is study showed that most errors pass unnoticed and are therefore not
reported. Measurement of error rates may constitute an important quali
ty indicator. Retrospective information of this survey to the concerne
d staff people provided an impetus to take adequate measures to reduce
these bedside errors.