LOCALIZED AMYLOIDOSIS FORTUITOUSLY DISCOV ERED UPON SURGERY - A RETROSPECTIVE REVIEW OF 10 CASES

Authors
GONTHIER R BOUCHOU K CATHEBRAS P DURAND DV POULARD G BOUCHERON S TOSTAIN J NINET J LEVRAT R ROUSSET H
Citation
R. Gonthier et al., LOCALIZED AMYLOIDOSIS FORTUITOUSLY DISCOV ERED UPON SURGERY - A RETROSPECTIVE REVIEW OF 10 CASES, La Semaine des hopitaux de Paris, 70(3-4), 1994, pp. 69-74
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
La Semaine des hopitaux de Paris → ACNP
ISSN journal
00371777
Volume
70
Issue
3-4
Year of publication
1994
Pages
69 - 74
Database
ISI
SICI code
0037-1777(1994)70:3-4<69:LAFDEU>2.0.ZU;2-O
Abstract
Ten cases of localized amyloidosis fortuitously discovered upon examin ation of operative specimens are reported. Three patients went on to d evelop systemic amyloidosis, whereas in the seven remaining patients t he deposits remained localized to the larynx (n= 2), cardiac valves (n = 1), bladder (n = 1), sciatic nerve (n= 1), eyelid (n = 1) or fallop ian tube (n = 1). The pathogenesis of localized amyloidosis is unclear , although presence of dystrophic lesions may be a risk factor. In mos t cases the deposits are composed of monoclonal light chains (AL type) .