TUBULAR INCLUSIONS IN MACROPHAGES IN THE BRAIN OF A PATIENT WITH ACUTE HEMORRHAGIC LEUKOENCEPHALITIS (WESTON-HURST SYNDROME)

A case history, biopsy findings, and autopsy findings of an unusually long-lasting case of acute hemorrhagic leukoencephalitis in a young wo man are presented. Diagnosis by stereotactic biopsy of brain lesions s een on computed tomography and magnetic resonance imaging scans had be en attempted previously. On histologic examination the biopsy showed s heets of macrophages, which were found to contain unusual tubular incl usions on electron microscopy. The nature of these inclusions is discu ssed.