PECULIAR MEMBRANOGRANULAR GLOMERULAR DEPOSITS

Two patients with immune complex diseases, one with IgA nephropathy an d the other with systemic lupus erythematosus, were found to have pecu liar membranogranular deposits in the glomeruli in addition to typical immune complex deposits. There was no clinical indication of familial lipidosis in either case. The deposits were very similar to those see n in lecithin-cholesterol acyltransferase-deficient patients. The path ogenetic role of lipid deposits in the glomerulus is discussed.