Rl. Yowell et Eh. Hammond, CARDIAC PARAPROTEIN ASSOCIATED WITH WALDENSTROMS MACROGLOBULINEMIA - A CASE-REPORT, Ultrastructural pathology, 18(1-2), 1994, pp. 229-232
A case of myocardial paraprotein deposition in a patient with Waldenst
rom's macroglobulinemia is presented. Routine light microscopy reveale
d diffuse widening of interstitial regions by pale eosinophilic materi
al that had a grayish cast on trichrome stains and was Congo red negat
ive. Immunofluorescence showed strong immunoglobulin M and k light cha
in staining around blood vessels but predominantly around myocytes. Ul
trastructural examination revealed massive deposition of flocculent el
ectron-dense material around myocytes and occasionally around blood ve
ssels.