M. Nagele et al., HEMOPHILIC ARTHROPATHY OF THE KNEE - GD-D TPA ENHANCED MRT - CLINICALAND RADIOLOGICAL CORRELATION, RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren, 160(2), 1994, pp. 154-158
17 patients with hemophilic arthropathy of the knee joint were studied
with static and dynamic MRT before and after i.v. bolus injection of
Gadolinium-DTPA (0,1 mmol/kg body weight). After contrast enhancement,
synovial proliferations exhibited an increase of signal intensity (SI
) on FFE and SE images of 47.7 % and 37.4 % respectively, whereas musc
le and fatty tissue, tendons, bone marrow and joint effusion revealed
only minor increase in SI. The gradient of signal intensity (ratio SI/
time) of pannus was 39,6%/min. Gd-DTPA enhanced MRI studies delineate
and quantify the synovial proliferations in hemophilic arthropathy. Dy
namic studies in hemophilic arthropathy do not provide qualitative ass
essment of the inflammatory process.