SECONDARY MYELODYSPLASTIC SYNDROME FOLLOWING BONE-MARROW TRANSPLANTATION - REPORT OF 2 CASES

Authors
CHAN T JUNEJA S WOLF M JANUSZEWICZ E COOPER I
Citation
T. Chan et al., SECONDARY MYELODYSPLASTIC SYNDROME FOLLOWING BONE-MARROW TRANSPLANTATION - REPORT OF 2 CASES, Bone marrow transplantation, 13(2), 1994, pp. 145-148
Citations number
10
Categorie Soggetti
Hematology,Oncology,Immunology
Journal title
Bone marrow transplantation → ACNP
ISSN journal
02683369
Volume
13
Issue
2
Year of publication
1994
Pages
145 - 148
Database
ISI
SICI code
0268-3369(1994)13:2<145:SMSFBT>2.0.ZU;2-K
Abstract
We report two cases of secondary myelodysplastic syndrome (SMDS) which followed successful treatment of a primary malignancy with high-dose chemotherapy supported by reinfusion of autologous stem cells. The SMD S was diagnosed 24 months and 40 months, respectively, following autog rafting. Both patients lived for 7 months after the diagnosis of SMDS. Our cases support the view that there is an increased risk of SMDS/ac ute leukemia following autologous marrow transplantation.