HYPERTHYROIDISM SECONDARY TO A PITUITARY-ADENOMA SECRETING TSH, FSH, ALPHA-SUBUNIT AND GH

Authors
PATRICK AW ATKIN SL MACKENZIE J FOY PM WHITE NC MACFARLANE IA
Citation
Aw. Patrick et al., HYPERTHYROIDISM SECONDARY TO A PITUITARY-ADENOMA SECRETING TSH, FSH, ALPHA-SUBUNIT AND GH, Clinical endocrinology, 40(2), 1994, pp. 275-278
Citations number
12
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Clinical endocrinology → ACNP
ISSN journal
03000664
Volume
40
Issue
2
Year of publication
1994
Pages
275 - 278
Database
ISI
SICI code
0300-0664(1994)40:2<275:HSTAPS>2.0.ZU;2-1
Abstract
A 51-year-old man had been treated for hyperthyroidism with antithyroi d drugs for 8 years. He was then found to have a large pituitary adeno ma with biochemical evidence of overproduction of TSH, FSH and alpha-s ubunit. Subsequent immunocytochemical and tissue culture studies confi rmed secretion of these hormones. In addition, the tumour stained for GH and was capable of GH production in vitro. This combination of horm ones produced by a pituitary adenoma has not been previously reported.