STRUCTURES OF 4 OLIGOSACCHARIDES DERIVED FROM THE GLYCOINOSITOLPHOSPHOLIPID OF LEISHMANIA-ADLERI

Authors
ROUTIER F MENDONCAPREVIATO L PREVIATO JO JONES C WAIT R
Citation
F. Routier et al., STRUCTURES OF 4 OLIGOSACCHARIDES DERIVED FROM THE GLYCOINOSITOLPHOSPHOLIPID OF LEISHMANIA-ADLERI, Brazilian journal of medical and biological research, 27(2), 1994, pp. 211-217
Citations number
10
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Brazilian journal of medical and biological research → ACNP
ISSN journal
0100879X
Volume
27
Issue
2
Year of publication
1994
Pages
211 - 217
Database
ISI
SICI code
0100-879X(1994)27:2<211:SO4ODF>2.0.ZU;2-0
Abstract
Glycoinositolphospholipids (GIPLs) were extracted from the trypanosoma tid Leishmania adleri by hot phenol extraction and the carbohydrate mo ieties isolated after base cleavage. Purification of the crude oligosa ccharides by high performance anion exchange (HPAE) chromatography yie lded four fractions whose structures were determined by a combination of methylation analysis, fast atom bombardment (FAB) mass spectrometry and two-dimensional nuclear magnetic resonance (NMR) spectroscopy.