IMMUNOHISTOCHEMICAL LOCALIZATION OF TYROSINE-HYDROXYLASE, SUBSTANCE-P, NEUROPEPTIDE-Y AND LEUCINE-ENKEPHALIN IN DEVELOPING HUMAN RETINAL AMACRINE CELLS

Authors
JOTWANI G ITOH K WADHWA S
Citation
G. Jotwani et al., IMMUNOHISTOCHEMICAL LOCALIZATION OF TYROSINE-HYDROXYLASE, SUBSTANCE-P, NEUROPEPTIDE-Y AND LEUCINE-ENKEPHALIN IN DEVELOPING HUMAN RETINAL AMACRINE CELLS, Developmental brain research, 77(2), 1994, pp. 285-289
Citations number
23
Categorie Soggetti
Neurosciences
Journal title
Developmental brain research → ACNP
ISSN journal
01653806
Volume
77
Issue
2
Year of publication
1994
Pages
285 - 289
Database
ISI
SICI code
0165-3806(1994)77:2<285:ILOTS>2.0.ZU;2-X
Abstract
Prenatal changes in the neurotransmitter/neuromodulator profiles of ty rosine hydroxylase (for dopamine), substance P, neuropeptide Y, and le ucine-enkephalin were studied in developing human retinal amacrine cel ls by the use of immunohistochemical techniques. Tyrosine hydroxylase was localized between 10 and 12 weeks of gestation, substance P and ne uropeptide Y appeared little later around 14 weeks, and leucine-enkeph alin-like immunoreactivity was observed at 16 weeks.