B. Bromley et al., COMPARISON BETWEEN SONOGRAPHIC MORPHOLOGY AND DOPPLER WAVE-FORM FOR THE DIAGNOSIS OF OVARIAN MALIGNANCY, Obstetrics and gynecology, 83(3), 1994, pp. 434-437
Objective: To assess the accuracy of pelvic sonography in distinguishi
ng benign from malignant lesions in postmenopausal women, using morpho
logic criteria and Doppler flow characteristics. Methods: All postmeno
pausal patients scanned from March 1992 to April 1993 with sonographic
ally identified and pathologically confirmed adnexal masses formed the
study group. The adnexal lesions were morphologically categorized pro
spectively as benign or malignant, and pulsed Doppler how studies were
measured using the lowest resistance index obtained from each mass. T
he sensitivity and specificity were determined for morphologic and Dop
pler flow assessments, as well as for a combination Of these methods,
for predicting the presence of malignancy. Results: Thirty-three postm
enopausal patients formed the study group; 12 lesions were malignant a
nd 21 were benign pathologically. Using morphologic criteria alone, th
e sensi tivity in detecting malignancy was 91% and specificity was 52%
. Using pulsed peppier alone with a resistance index limit of 0.6, the
sensitivity in predicting malignancy was 66%, with a specificity of 8
1%. If a resistance index limit of 0.8 were used, the sensitivity and
specificity would be the same as those for morphology alone. Combining
morphology and resistance index, a single malignancy would still have
been missed (sensitivity 91%). Conclusion: In our experience, Doppler
flow studies did not add substantially to the prediction of malignanc
y using morphologic assessment alone.