CONSTITUENTS OF EUPHORBIACEAE .11. ISOLATION AND STRUCTURE ELUCIDATION OF 7 CEREBROSIDES FROM EUPHORBIA-WULFENII HOPPE EX KOCH

Seven cerebrosides C1-C5, C2a and C3a have been isolated from the late x of Euphorbia wulfenii Hoppe ex Koch and their structures have been d etermined on the bet-sis of chemical and spectroscopic evidences. Norm al and reversed phase flash-chromatography was effective for the isola tion of the cerebrosides. FAB-MS spectrometry, H-1-NMR, C-13-NMR analy sis and chemical reactions were useful in providing informations for t heir structure elucidation. EI-MS of the dimethyl disulfide derivative s of the FAMs has been decisive for the determination of the double bo nd position in the fatty acids. The cerebrosides isolated from Euphorb ia wulfenii show very close similarities in their structures.