LIQUID AND GAS-CHROMATOGRAPHIC MULTI-RESIDUE PESTICIDE DETERMINATION IN ANIMAL-TISSUES

A liquid chromatography multi-residue method with photometric detectio n has been developed. The method is applicable to the quantitative det ermination of organochlorine (tetradifon, dicofol, chlorfenson, chloro benzilate), organophosphorus (fenitrothion, azinphos-ethyl) and carbam ate (pirimicarb) pesticides in animal tissues. The extracted residues are cleaned up by gel-permeation chromatography. A further fractionati on on silica Sep-Pack cartridges is included in the procedure. A gas c hromatographic method with electron-capture detection for the analysis of the same pesticides was carried out and the results in the two cas es compared. Lower detection and quantitation limits and similar recov eries of pesticides from spiked pig liver and brain samples were obtai ned by the LC method.