HYDROXY-DIRECTED HYDROALUMINATIONS - A STEREOSELECTIVE APPROACH TO CYCLOALKANOLS FROM BETA-ARYL ENONES

Authors
KOCH K SMITROVICH JH
Citation
K. Koch et Jh. Smitrovich, HYDROXY-DIRECTED HYDROALUMINATIONS - A STEREOSELECTIVE APPROACH TO CYCLOALKANOLS FROM BETA-ARYL ENONES, Tetrahedron letters, 35(8), 1994, pp. 1137-1140
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
8
Year of publication
1994
Pages
1137 - 1140
Database
ISI
SICI code
0040-4039(1994)35:8<1137:HH-ASA>2.0.ZU;2-G
Abstract
Various aryl substituted enones are reduced using lithium aluminum hyd ride to afford sterioselectively trans substituted alkanols. Mechanist ic studies demonstrate 1,2 addition followed by hydroxy-directed hydro alumination of the conjugated styryl unit.