PREPARATION OF NOVEL HEXYTHIAZOX ANALOGS

Authors
NOVAK L HORNYANSZKY G ROHALY J KOLONITS P SZANTAY C
Citation
L. Novak et al., PREPARATION OF NOVEL HEXYTHIAZOX ANALOGS, Pesticide science, 49(1), 1997, pp. 85-89
Citations number
8
Categorie Soggetti
Agriculture
Journal title
Pesticide science → ACNP
ISSN journal
0031613X
Volume
49
Issue
1
Year of publication
1997
Pages
85 - 89
Database
ISI
SICI code
0031-613X(1997)49:1<85:PONHA>2.0.ZU;2-B
Abstract
Novel analogues of the title compound were prepared in several steps: via addition of methylmagnesium iodide to an acetamide derivative to y ield diastereomeric amino alcohols, followed by hydrolysis, cyclizatio n to the corresponding oxazole or thiazole derivative, and a coupling reaction with isocyanates. Results from acaricidal tests showed the co mpounds to be 100 times less active than hexythiazox.