DIABETIC SCLEREDEMA AND SCLERODERMA-LIKE CHANGES IN A PATIENT WITH MATURITY-ONSET TYPE DIABETES OF YOUNG-PEOPLE

A 21-year-old housewife with maturity onset type diabetes of young peo ple developed scleredema diabeticorum, scleroderma-like skin thickness on forearms and dorsum of hands, digital sclerosis and cheiroarthropa thy. She had diabetes mellitus since the age of 11 years. Her grandfat her on the mother's side, her mother and 3 of 5 her mother's brothers and sisters have diabetes mellitus. Blood glucose was 295 mg/dl. Urina ry glucose was 5.3 g/day. Nail fold capillary microscopy revealed a pr ogressive systemic sclerosis pattern. Histologically, hematoxylin and eosin sections from back and forearm skin demonstrated broad collagen bundles separated by widened clear spaces throughout the thickened der mis.