The fruit extracts of Ficus sycomorus L., F. benjamina L., F. bengalen
sis L. and F. religiosa L. were screened for bioactivity. F. bengalens
is and F. religiosa demonstrated activity in the brine shrimp test (Ar
temia salina) which indicates toxicity, whereas F. sycomorus and F. be
njamina showed no activity. All the fruit extracts exhibited antitumor
activity in the potato disc bioassay. None of the tested extracts sho
wed any marked inhibition on the uptake of calcium into rat pituitary
cells GH(4)C(1). The extracts of the four tested Ficus species had sig
nificant antibacterial activity, but no antifungal activity. The resul
ts of this preliminary investigation support the traditional use of th
ese plants in folk medicine for respiratory disorders and certain skin
diseases.