SUCCESSFUL ADMINISTRATION OF LOW-MOLECULAR-WEIGHT HEPARIN IN A PATIENT WITH HEPARIN-INDUCED THROMBOCYTOPENIA AND COUMARIN-INDUCED SKIN NECROSIS

A case of heparin-induced thrombocytopenia and skin necrosis induced b y coumarin is reported in a 58-year-old female patient suffering from metastatic breast adenocarcinoma and deep vein thrombosis. The thrombo sis resolved after treatment with low molecular weight heparin and the thrombocytopenia recovered within a few days. The occurrence of both these rare complications in the same patient has not been previously r eported in the literature. We present a review of these complications and their current treatment.