ANTITUMOR ACTIVITIES OF LEVANS PRODUCED BY ZYMOMONAS-MOBILIS STRAINS

Authors
CALAZANS GMT LOPES CE LIMA RMOC DEFRANCA FP
Citation
Gmt. Calazans et al., ANTITUMOR ACTIVITIES OF LEVANS PRODUCED BY ZYMOMONAS-MOBILIS STRAINS, Biotechnology letters, 19(1), 1997, pp. 19-21
Citations number
15
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
19
Issue
1
Year of publication
1997
Pages
19 - 21
Database
ISI
SICI code
0141-5492(1997)19:1<19:AAOLPB>2.0.ZU;2-2
Abstract
Levans produced by four Zymomonas mobilis strains showed antitumour ac tivity against sarcoma 180 and Ehrlich carcinoma in Swiss albino mice. Levans from two strains (ZAP and CP4) had the highest effects. NMR an alysis showed that the polymers were composed only of fructose units. The results suggested that the antineoplasic effect is associated to t he polysaccharide molecular weight and that a particular molecular wei ght range may be responsible for this effect.