Ar. Butcher et al., COCCIDIAN CYANOBACTERIUM-LIKE BODY ASSOCIATED DIARRHEA IN AN AUSTRALIAN TRAVELER RETURNING FROM OVERSEAS/, Pathology, 26(1), 1994, pp. 59-61
Coccidian/cyanobacterium-like body (CLB) associated diarrhea occurred
in a 42 yr old Australian woman returning from Ball, Indonesia. The pa
tient had a diarrheal illness of 10 days duration with symptoms of exp
losive diarrhea, nausea, anorexia and fever. Fecal examination reveale
d CLBs which were detected in modified Ziehl-Neelsen stained fecal sme
ars. No other bacterial or parasite pathogens were found. CLBs were va
riably acid fast, showed an intense blue auto-fluorescence under UV mi
croscopy and appeared as non-refractile hyaline spheres in direct wet
mounts, being 8-9 um in diameter. The taxonomic status of CLBs has bee
n unclear but recent evidence supports that they are a coccidian paras
ite of the genus Cyclospora, rather than cyanobacterium. There is no s
pecific therapy for CLB enteritis and spontaneous recovery occurs afte
r what may be a prolonged diarrheal illness. CLBs may be a previously
unrecognized enteric pathogen although their role in the pathology of
diarrheal illness is still undetermined. There is consistency in the c
linical and laboratory findings amongst the reported cases and CLBs sh
ould be considered in persons with unexplained gastroenteritis, especi
ally travellers returning from tropical regions.