Thirteen trained runners were studied to determine whether postexercis
e glucose ingestion contributes to electrocardiogram (ECG) alterations
by enhancing decreases in serum potassium (K+) concentrations. For th
e two randomly ordered trials, subjects ingested a 100 g (25% w/v gluc
ose polymer) drink, either alone or with the addition of 3 g of potass
ium chloride (KCl), within 15 min following a 90-min run. ECG paramete
rs, serum K+, and glucose concentrations were measured preexercise (Ti
me 0), 2-3 min postexercise (Time 1), and 25 (Time 2) and 60 (Time 3)
min postexercise. The data suggest that postexercise glucose ingestion
may cause ECG changes that are not directly related to the return of
K+ to muscle, and that these changes, although characteristic of hypok
alemia, may be related to serum glucose excursions rather than to abso
lute levels of serum K+. The addition of KCl may have prevented these
changes by delaying gastric emptying of glucose.