A CASE OF TRANSIENT HYPERPHOSPHATASEMIA FOLLOWING VITAMIN-D - DEFICIENT RICKETS

A seven-month-old boy with a diagnosis of vitamin-D deficiency rickets is presented. After treatment with vitamin-D, biochemical and radiolo gical improvement was noted. At 14-months of age the plasma akaline ph osphatase activity valve was found to be elevated even though rickets was not present. A diagnosis of hyperphosphatasemia was established. A lthough rare in infancy, transient hyperphospha tasemia may occur foll owing vitamin-D deficient rickets. This possibility should be consider ed when evaluating laboratory results in such cases.