MAGNETIC-RESONANCE EVALUATION OF DISEASE-ACTIVITY DURING PREGNANCY INMULTIPLE-SCLEROSIS

We followed two women with MS during pregnancy by means of serial unen hanced MR imaging. On each follow-up image, we assessed the number of new or enlarging lesions. Both women showed a decrease in MR disease a ctivity during the second half of pregnancy and a return of MR disease activity to prepregnancy levels in the first months postpartum. These findings support the view that pregnancy reduces disease activity in MS.