INTERMITTENT ENCEPHALOPATHY, REVERSIBLE NERVE-CONDUCTION SLOWING, ANDMRI EVIDENCE OF CEREBRAL WHITE-MATTER DISEASE IN METHYLENETETRAHYDROFOLATE REDUCTASE DEFICIENCY

Authors
WALK D KANG SS HORWITZ A
Citation
D. Walk et al., INTERMITTENT ENCEPHALOPATHY, REVERSIBLE NERVE-CONDUCTION SLOWING, ANDMRI EVIDENCE OF CEREBRAL WHITE-MATTER DISEASE IN METHYLENETETRAHYDROFOLATE REDUCTASE DEFICIENCY, Neurology, 44(2), 1994, pp. 344-347
Citations number
9
Categorie Soggetti
Clinical Neurology
Journal title
Neurology → ACNP
ISSN journal
00283878
Volume
44
Issue
2
Year of publication
1994
Pages
344 - 347
Database
ISI
SICI code
0028-3878(1994)44:2<344:IERNSA>2.0.ZU;2-Q
Abstract
We describe a patient with methylenetetrahydrofolate reductase (MTHFR) deficiency in whom clinical and electrophysiologic fluctuations paral leled exacerbations of hyperhomocyst(e)inemia. MRI demonstrated abnorm alities characteristic of a leukodystrophy.