Rt. Echols et Jf. Tyson, COMPARISON OF MIXING DEVICES FOR FLOW-INJECTION DETERMINATIONS BASED ON DOUBLET PEAK FORMATION, Analytica chimica acta, 286(2), 1994, pp. 169-178
The well-stirred tank model accurately describes the separation (Delta
t) between flow-injection doublet peaks and has been found to be appl
icable to a variety of mixing devices that do not contain moving parts
such as a magnetic follower. The reaction between lanthanum(III) and
methyl thymol blue was used as a model reaction for a comparison study
of mixing devices. Column and open-tubular reactors were included in
the study. Mixing devices were compared on the basis of the straight l
ine fit of Delta t versus the natural logarithm of the concentration o
f injected La(III). The linearity of the Delta t-ln[La(III)] plots was
equivalent for several reactors. A mixing device composed of a column
of alternating helices was selected as the best alternative mixer to
the well-stirred tank when the magnitude of the slope of the plot and
practicality were considered. Experiments showed that the well-stirred
tank model qualitatively describes the behavior of these alternating
helical reactors (AHR) in experiments designed to produce doublet peak
s. The AHR was used as the mixing device in flow-injection determinati
ons, based on doublet peaks, of zinc, hydroxide ion and of water hardn
ess. A paired t-test showed that over the 16 determinations performed
there was no significant bias at the 95% confidence level. Factors aff
ecting the relative standard deviation of the concentrations measured
are discussed.